| Friday, September 8th | ||
| Indiana State at Indiana | 6:00 PM | BTN |
| Illinois at Kansas | 6:30 PM | ESPN2 |
| Saturday, September 9th | | |
| Vanderbilt 20 Wake Forest 36 | ||
| Ball State 3 Georgia 45 | ||
| Delaware State 0 Army 57 | ||
| James Madison at Virginia | 11:00 AM | ESPNU |
| Nebraska 14 Colorado 36 | ||
| Notre Dame 45 NC State 24 | ||
| Purdue at Virginia Tech | 11:00 AM | ESPN2 |
| Troy 13 Kansas State 42 | ||
| Utah 20 Baylor 13 | ||
| Youngstown State 7 Ohio State 35 | ||
| Charleston Southern 17 Clemson 66 | ||
| Iowa at Iowa State | 2:30 PM | FOX |
| Ole Miss 37 Tulane 20 | ||
| Richmond at Michigan State | 2:30 PM | BTN |
| Texas A&M 33 Miami 48 | ||
| UNLV 7 Michigan 35 | ||
| Wagner 0 Navy 24 | ||
| Kent State at Arkansas | 3:00 PM | SECN |
| Marshall at East Carolina | 3:00 PM | ESPNU |
| Tulsa 10 Washington 43 | ||
| Appalachian State 34 North Carolina 40 | ||
| Houston at Rice | 6:00 PM | NFL Network |
| Oregon 38 Texas Tech 30 | ||
| Texas 34 Alabama 24 | ||
| UCF at Boise State | 6:00 PM | FS1 |
| Arizona at Mississippi State | 6:30 PM | SECN |
| Charlotte at Maryland | 6:30 PM | NBC |
| Eastern Michigan at Minnesota | 6:30 PM | BTN |
| McNeese 7 Florida 49 | ||
| UCLA at San Diego State | 6:30 PM | CBS |
| Wisconsin 22 Washington State 31 | ||
| Air Force at Sam Houston | 7:00 PM | CBSSN |
| Southern Miss at Florida State | 7:30 PM | ACCN |
| UC Davis at Oregon State | 8:00 PM | Pac-12 |
| Auburn at Cal | 9:30 PM | ESPN |
| Oklahoma State at Arizona State | 9:30 PM | FS1 |
| Stanford at USC | 9:30 PM | FOX |